LARAMIE, Wyo.  (Sept. 8, 2025) – The Wyoming Cowboys head south for a matchup with the Colorado Buffaloes on Sept. 20. The Big 12 Conference announced on Monday that contest is set for an 8:15 p.m. MT kick on ESPN.

The last time the two teams played was in 2009 in Boulder.  The series between the two schools dates back to Nov. 10, 1900, when they first played a game at Colorado.